Xiahong Xu

Visiting Professors

Contact Information

  • Email Address: xiahong.xu@duke.edu

Education

  • 2008-2011 Hunan University (State Key Laboratory of Chem/Biosensing and Chemometrics), Ph.D. in Analytic Chemistry, Advisor: Shouzhuo Yao
  • 2006-2008 Hunan University (State Key Laboratory of Chem/Biosensing and Chemometrics), M.S. in Analytic Chemistry, Advisor: Shouzhuo Yao
  • 2002-2006 Hunan Normal University, B.S. in Chemistry

Research Interests

Nanomaterirals based biosensor

Food safety

Electrochemistry

Fluorescence analysis 

Professional Experiences:

Dec. 2018 - Present,

Visiting Scholar at Department of Mechanical Engineering and Materials Science (MEMS), Duke University.

Nov. 2014 – Present,

Institute of Quality and Standard for Agricultural Products. Hangzhou Center of Inspection and Testing for Quality and Safety of Agricultural and Genetically Modified Products, Ministry of Agriculture and Rural Affairs. Hangzhou Lab of Risk Assessment for Quality and safety of Agricultural Products, Ministry of Agriculture. Key Laboratory for Pesticide Residue Detection, Ministry of Agriculture and Rural Affairs, Associate Professor

Mar. 2012 – Oct. 2014,

College of Biosystem Engineering and Food Science, Agricultural Engineering Dept., Zhejiang University, Research Assistant

Awards:

1. Outstanding Young Agricultural Scientist, Ministry of Agriculture and Rural Affairs, China. 2018.

2. The excellent doctoral thesis in Hunan province, 2014.

Patents:

1. Xiahong Xu, Xinquan Wang, Yuwei Yuan, Guixian Hu, Jiahong Zhu, Xiangyun Wang, Peipei Qi, Zhiwei Wang, Qiang Wang, Hua Yang. 2018, China, ZL 201610395529.7

2. Xiahong Xu, Qinqin Hu, Ying Zhang, Yanbin Li. 2015, China,ZL201310383303.1

Publications

1.      Kaiyu He, Zhishang Li, Liu Wang, Yingchun Fu, Haoran Quan, Yanbin Li, Xinquan Wang, Sundaram Gunasekaran, Xiahong Xu*, A Water-stable Luminescent Metal-organic Framework for Rapid and Visible Sensing of Organophosphorus Pesticides, ACS Applied Materials & Interfaces, 2019, 11(29), 26250-26260.

2.      Kaiyu He, Hua Yang, Liu Wang, Jiehao Guan, Min Wu, Hongmei He, Sundaram Gunasekaran, Xinquan Wang, Qiang Wang, Xiahong Xu*. A universal platform for multiple logic operations based on self-assembled a DNA tripod and graphene oxide. Chemical Engineering Journal 2019 (368), 877–887.

3.      Zhishang Li, Xiahong Xu, Yingchun Fu, Yuna Guo, Qiaoyan Zhang, Hua Yang and Yanbin Li, Water-stable luminescent metal-organic framework for effective detection of Aflatoxin B1 in walnut and almond beverages, RSC Adv., 2019, 9, 620-625.

4.      Xiahong Xu, Yuna Guo, Liu Wang, Kaiyu He, Yirong Guo*, Xinquan Wang*, and Sundaram Gunasekaran. Hapten-Grafted Programmed Probe as Corecognition Element for Competitive Immunosensor to Detect Acetamiprid Residue in Agricultural Products, J. Agric. Food Chem., 2018, 66 (29), 7815–7821.

5.      Xiahong Xu, Yuna Guo, Xiangyun Wang, Wang Li, Peipei Qi, Zhiwei Wang, Xinquan Wang*, Sundaram Gunasekaran and Qiang Wang, Sensitive Detection of Pesticides by a Highly Luminescent Metal-organic Framework, Sensors and Actuators B: Chemical, 2018, 260, 339-345.

6.      Hua Yang, Xin Qi, Xinquan Wang, Xiangyun Wang, Qiang Wang, Peipei Qi, Zhiwei Wang, Xiahong Xu*, Yingchun Fu*, Shouzhuo Yao. Regulating Immobilization Performance of Metal-organic Coordination Polymers through Pre-coordination for Biosensing. Analytica Chimica Acta, 2018, 1005, 27-33.

7.      Zhiwei Wang, Xinquan Wang, Tao Cang, Xueping Zhao, Shenggan Wu, Peipei Qi, Xiangyun Wang, Xiahong Xu, Qiang Wang. Positive effects of an oil adjuvant on efficacy, dissipation and safety of pyrimethanil and boscalid on greenhouse strawberry. Ecotoxicology and Environmental Safety, 2018, 160, 127-133.

8.      Peipei Qi, Jiao Wang, Zhiwei Wang, Xue Wang, Xiangyun Wang, Xiahong Xu, Hao Xu, Shanshan Di, Hu Zhang, Qiang Wang. Construction of a probe-immobilized molecularly imprinted electrochemical sensor with dual signal amplification of thiol graphene and gold nanoparticles for selective detection of tebuconazole in vegetable and fruit samples. Electrochimica Acta. 2018, 274, 406-414.

9.      Yuhan Sun, Peipei Qi, Tao Cang, Zhiwei Wang, Xiangyun Wang, Xuewei Yang, Lidong Wang, Xiahong Xu, Qiang Wang, Xinquan Wang. High-throughput multipesticides residue analysis in earthworms by the improvement of purification method: Development and application of magnetic Fe3O4-SiO2. Journal of Separation Science, 2018, https://doi.org/10.1002/jssc.201701296.

10.   Xuewei Yang, Peipei Qi, Xiangyun Wang, Zhiwei Wang, Yuhan Sun, Lidong Wang, Xiahong Xu, Hao Xu, Qiang Wang, Xinquan Wang. Stereoselective Analysis and Degradation of Pyrisoxazole in Cabbage, Pakchoi, and Pepper by Liquid Chromatography Tandem Mass Spectrometry. Journal of Agricultural and Food Chemistry, 2017, 65, 38, 8295-8301.

11.   Xinquan Wang, Peipei Qi, Xiangyun Wang, Qian Zhang, Zhiwei Wang, Xiahong Xu, Hao Xu, Hu Zhang, Qiang Wang. An efficient cleanup method coupled with gas chromatography and mass spectrometry for multi-pesticides residue analysis in complex plant matrices. Journal of Separation Science, 2017, 40, 11, 2438-2450.

12.   Zhuoliang Liu, Kaiyu He, Wang Li, Xin Liu, Xiahong Xu, Zhou Nie, Shouzhuo Yao. DNA G-Quadruplex-Based Assay of Enzyme Activity. 3D DNA Nanostructure. 2017, 133-151.

13.   Zhenzhen Liu, Peipei Qi, Xiangyun Wang, Zhiwei Wang, Xiahong Xu, Wenxue Chen, Liyu Wu, Hu Zhang, Qiang Wang, Xinquan Wang. Multi-pesticides residue analysis of grains using modified magnetic nanoparticle adsorbent for facile and efficient cleanup. Food Chemistry, 2017, 230, 423-431.

14.   Xiahong Xu, Yuwei Yuan, Guixian Hu, Xiangyun Wang, Peipei Qi, Zhiwei Wang, Qiang Wang*, Xinquan Wang*, Yingchun Fu, Yanbin Li, Hua Yang.Exploiting pH-Regulated Dimer-Tetramer Transformation of Concanavalin A to Develop Colorimetric Biosensing of Bacteria. Scientific Reports, 2017, 7: 1452.

15.   Xiahong Xu, Xin Qi, Xinquan Wang, Xiangyun Wang, Qiang Wang, Hua Yang*, Yingchun Fu*, Shouzhuo Yao. Highly Efficient Enzyme Immobilization by Nanocomposites of Metal Organic Coordination Polymers and Carbon Nanotubes for Electrochemical Biosensing. Electrochemistry Communications, 2017, 79, 18-22.

16.   Qinqin Hu, Yingchun Fu, Xiahong Xu*, Zhaohui Qiao, Ronghui Wang, Ying Zhang, Yanbin Li*, A colorimetricdetectionofacrylamideinpotatochipsbasedonnucleophile-initiatedthiol-eneMichaeladdition, Analyst, 2016,141(3):1136-1143

17.   Qinqin Hu, Xiahong Xu, Yingchun Fu, Yanbin Li*, Rapid methods for detecting acrylamide in thermally processed foods: A review, Food Control, 2015, 56:135-146

18.   Chunyang Lei#, Xiahong Xu#, Jiang Zhou, Xin Liu, Zhou Nie*, Meng Qing, Pei Li, Yan Huang*, Shouzhuo Yao, A mix-and-read fluorescence strategy for the switch-on probing of kinase activity  based on an aptameric-peptide/graphene-oxide platform. Chemistry - An Asian Journal, 2014, 9(9):2560-2567

19.   Qinqin Hu, Xiahong Xu, Zhanming Li, Ying Zhang, Jianping Wang, Yingchun Fu, Yanbin Li*, Detection of acrylamide in potato chips using a fluorescent sensing method based on acrylamide polymerization- induced distance increase between quantum dots, Biosensors and Bioelectronics, 2014, 54:64-71

20.   Xin Liu, Yong Li, Xiahong Xu, Pei Li, Zhou Nie*, Yan Huang, Shouzhuo Yao, Nanomaterial-based tools for protein kinase bioanalysis, TrAC-Trends in Analytical Chemistry, 2014, 58:40-53.

21.   Jiang Zhou, Xiahong Xu, Xin Liu, Hao Li, Zhou Nie*, Meng Qing, Yan Huang, Shouzhuo Yao, A gold nanoparticles calorimetric assay for label-free detection of protein kinase activity based on phosphorylation protection against exopeptidase cleavage, Biosensors and Bioelectronics, 2014, 53:295-300

22.   Lizhou Xu, Xiahong Xu, Hua Xiong, Lingxin Chen, Yanbin Li*, Rapid detection of vegetable cooking oils adulteratedwithinedibleusedoilusingfluorescencequenchingmethodwithaqueousCTAB-coatedquantum dots, Sensors and Actuators B: Chemical, 2014, 203:697-704

23.   Jiang Zhou#, Xiahong Xu#, Wei Liu, Xin Liu, Zhou Nie*, Meng Qin, Lihua Nie, Shouzhuo Yao, Graphene Oxide-Peptide Nanocomplex as a Versatile Fluorescence Probe of Protein Kinase Activity Based on Phosphorylation Protection against Carboxypeptidase Digestion, Analytical Chemistry, 2013, 85(12): 5746- 5754

24.   Jiang Zhou, Xiahong Xu, Xin Liu, Hao Li, Zhou Nie*, Meng Qing, Yan Huang, Shouzhuo Yao, A gold nanoparticles colorimetric assay for label-free detection of protein kinase activity based on phosphorylation protection against exopeptidase cleavage, Biosensors and Bioelectronics, 2013, 53:295-300

25.   Peng Zhao,Lifen Zhou,ZhouNie*,XiahongXu,WangLi,YanHuang,KaiyuHe,ShouzhuoYao,Versatile Electrochemiluminescent Biosensor for Protein-Nucleic Acid Interaction Based on the Unique Quenching Effect of Deoxyguanosine-5'-phosphate on Electrochemiluminescence of CdTe/ZnS Quantum Dots, Analytical Chemistry, 2013, 85(13):6279-6286

26.   Hui Lin,Lijun Li,Chunyang Lei,Xiahong Xu,Zhou Nie,Manli Guo,Yan Huang*,Shouzhuo Yao,Immune- independent and label-free fluorescent assay for Cystatin C detection based on protein-stabilized Au nanoclusters, Biosensors and Bioelectronics, 2013, 41:256-261

27.   XiahongXu,JiangZhou,XinLiu,ZhouNie*,MengQin,ManliGuo,ShouzhuoYao,AptamericPeptidefor One-Step Detection of Protein Kinase, Analytical Chemistry, 2012, 84(11):4746-4753

28.   Xiahong Xu, Xin Liu, Zhou Nie*, Yuliang Pan, Manli Guo, Shouzhuo Yao, Label-Free Fluorescent Detection of Protein Kinase Activity Based on the Aggregation Behavior of Unmodified Quantum Dots, Analytical Chemistry, 2011, 83(1):52-59

29.   WangLi,ZhouNie*,KaiyuHe,XiahongXu,YongLi,YanHuang,ShouzhuoYao,Simple,rapidandlabel- free colorimetric assay for Zn(2+) based on unmodified gold nanoparticles and specific Zn(2+) binding peptide, Chemical Communications, 2011, 47(15):4412-4414

30.   Xiahong Xu, Zhou Nie*, Jinhua Chen*, Yingchun Fu, Wang Li, Qinpeng Shen, Shouzhuo Yao, A DNA- based electrochemical strategy for label-free monitoring the activity and inhibition of protein kinase, Chemical Communications, 2009, (45):6946-6948

31.   Yingchun Fu,Penghao Li,Ting Wang,Lijuan Bu,Qingji Xie*,Xiahong Xu,Lihong Lei,Can Zou,Jinhua Chen, Shouzhuo Yao, Novel polymeric bionanocomposites with catalytic Pt nanoparticles label immobilized for high performance amperometric immunoassay, Biosensors and Bioelectronics, 2010, 25(7): 1699-1704

32.   WangLi,ZhouNie*,XiahongXu,QinpengShen,ChunyanDeng,JinhuaChen*,ShouzhuoYao,Asensitive, label free electrochemical aptasensor for ATP detection, Talanta, 2009, 78(3):954-958

33.   MengDong Wang, ChunYan Deng, Zhou Nie*, Xiahong Xu, ShouZhuo Yao, The direct electrochemistry of glucose oxidase based on the synergic effect of amino acid ionic liquid and carbon nanotubes, Science in China Series B-Chemistry, 2009, 52(11):1991-1998

34.   Lihong Lei, Yingchun Fu, Xiahong Xu, Qingji Xie, Shouzhuo Yao. Aptamer-based electrochemical biosensors, Progress in Chemistry, 2009, 21, 4, 724-731

35.   Xiahong Xu, Jinhua Chen*, Wang Li, Zhou Nie*, Shouzhuo Yao, Surface nanocrystallization of glassy carbon electrode: Application in direct electrochemistry of glucose oxidase, Electrochemistry Communications, 2008,10(10):1459-1462

36.   Yingchun Fu, Qingji Xie, Xiahong Xu, Wenhua Meng, Shouzhuo Yao. Electrosynthesized poly (1, 6-hexanedithiol) as a new immobilization matrix for Au-nanoparticles-enhanced piezoelectric immunosensing. Journal of Electroanalytical Chemistry, 2007, 603, 1, 96-106.

37.   Chunyan Deng, Mingrui Li, Qingji Xie, Meiling Liu, Yueming Tan, Xiahong Xu, Shouzhuo Yao.       New glucose biosensor based on a poly (o-phenylendiamine)/glucose oxidase-glutaraldehyde/Prussian blue/Au electrode with QCM monitoring of various electrode-surface modifications. Analytica Chimica Acta. 2006, 557, 85-94.

Book Chapters

1.  Xin Liu, Wang Li, Xiahong Xu, Jiang Zhou, Zhou Nie*, Electrochemical Aptamer Sensor for Small Molecule Assays, Methods in molecular biology, John M. Walker, Springer, pp 119-132, U.S., 10/01/2011.